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Rational Phytotherapy: A Reference Guide for Physicians and Pharmacists

volker schulz and Rudolf Hansel
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Phytomedicine 11, in press Siegel G, Nuck R, Schnalke F, Michel F (1998) Molecular evidence for phytopharmacological K+ channel opening by garlic in human vascular smooth muscle cell membranes. phytotherapy research 12:149-151. Siegel G, Walter A, Engel S, Walper A, Michel F (1999) Pleiotrope Wirkungen von Knoblauch. Wiener Med Wschr 149.217-224. Siegers P, Robke A, Pentz R (1999) Effects of garlic preparations on superoxide production by phorbol ester activated granulocytes. Phytomedicine 6:13-16. Silagy C, Neil A (1994) A meta-analysis of the effect of garlic on blood pressure.

The Inflammation Syndrome: The Complete Nutritional Program to Prevent and Reverse Heart Disease, Arthritis, Diabetes, Allergies, and Asthma

Jack Challem
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One intriguing European study, published in phytotherapy research, found that supplements of the flavonoid-containing Pycnogenol significantly reduced markers of inflammation and disease activity in patients with lupus. Patients taking corticosteroids to suppress inflammatory symptoms benefited from greater reductions in symptoms after adding 120 mg daily of Pycnogenol, and they also had reductions in their sedimentation rate, a general indicator of inflammation. It is possible that grape seed extract and other flavonoids might be beneficial as well. What Else Might Help?

The ABC Clinical Guide to Herbs

Mark Blumenthal
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Kava kava in the treatment of generalized anxiety disorder, simple phobia and specific social phobia. phytotherapy research 2001;15(7):646-7. Bone K. Kava—A safe herbal treatment for anxiety. Brit J Phytotherapy 1993/94:3(4): 147-153. Boonen G, Haberlein H. Influence of genuine kavapyrone enantiomers on the GABA-A binding site. Planta Medica 1998;64(6):504-506. Boonen G, Ferger B, Kuschinsky K, Haberlein H.

The Woman's Encyclopedia of Natural Healing

Dr. Gary Null
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Euphytose, an Association of Plant Extracts with Anxiolytic Activity: Investigation of its Mechanism of Action by an In Vitro Binding Study," phytotherapy research 5 (1991): 241-44. Passiflora edulis aqueous extract was the subject of a study involving rats, mice, and healthy human volunteers. It was shown to have a nonspecific depressant effect on the central nervous system, and not a hypnotic-sedative effect. E. Maluf et al., "Assessment of the Hypnotic/Sedative Effects and Toxicity of Passiflora Edulis Aqueous Extract in Rodents and Humans," phytotherapy research 5 (1991): 262-66.

The Encyclopedia of Popular Herbs

Robert S. McCaleb, Evelyn Leigh, and Krista Morien
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Phar-maton capsules in the treatment of functional fatigue: a double-blind study versus placebo evaluated by a new methodology. phytotherapy research 1996; 10:49-53. Wiklund I, Karlberg J, Lund B. A double-blind comparison of the effect on quality of life of a combination of vital substances including standardized ginseng G115 and placebo. Current Therapeutic Research 1994; 55(1): 32-42. Bhattacharya SK, Mitra SK. Anxiolytic activity of Panax ginseng roots: an experimental study. Journal of Ethnopharmacology 1991; 34: 87-92. 19. Yun T-K, Choi SY.
Immunomodulatory activity of boswellic acids (pentacyclic triterpene acids) from Boswellia serrata. phytotherapy research 1996; 10(2): 107-112. 12. Safayhi H, MackT, Ammon HPT. Protection by boswellic acids against galac-tosamine/endotoxin-induced hepatitis in mice. Biochemical Pharmacology 1991; 41 (10): 1536-1537. 13. Safayhi H, Mack T, Sabieraj J, et al. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. The Journal of Pharmacology and Experimental Therapeutics 1992; 261(3): 1143-1146. 14. McGuffm M, Hobbs C, Upton R, et al., eds.

Prevention's New Foods for Healing: Capture the Powerful Cures of More Than 100 Common Foods

Prevention Magazine
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American phytotherapy research Laboratory in Salt Lake City, 36 motion sickness-prone students were strapped into tilted rotating chairs and spun until they felt ill. Those who were given 100 milligrams of dimenhydrinate (Dramamine) beforehand couldn't take the stomach-churning ride for more than about AVi minutes, and most gave up sooner. Half of those given ginger, however, were able to withstand the ride for the full 6 minutes, with less nausea and dizziness than the drug-treated group.
American phytotherapy research Laboratory in Salt Lake City. Dr. Mowrey has studied the calming effects of ginger on thousands of motion sickness sufferers. What's more, he has firsthand knowledge of how well it works. He gives it to his own kids. "When we get in the car to take a trip, if they forgot their ginger root, they're out of it," Dr. Mowrey says. "When they have it, they're just fine." For minor motion sickness, having ginger ale, ginger snaps, or ginger tea before and during the trip can help settle your stomach, Dr. Mowrey says.
American phytotherapy research Laboratory in Salt Lake City. Here's what he recommends. Licorice root. This sweet-tasting herb, which you can use to make tea, is a natural anti-inflammatory that can help relieve irritation in the bowel, Dr. Mowrey says. Peppermint. In one study, people with IBS who took peppermint capsules were able to eliminate all or most of their symptoms, Dr. Mowrey says. Peppermint tea is also effective, he adds. Psyllium.

Prevention's Healing With Vitamins : The Most Effective Vitamin and Mineral Treatments for Everyday Health Problems and Serious Disease

The Editors of Prevention Magazine Health Books
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American phytotherapy research Laboratory in Lehi, Utah, points to a few foods that might help. Eat foods that go with the flow. Certain foods have anti-clotting properties, says Dr. Mowrey. "They may reduce the tendency for blood platelets to stick together or to the sides of blood vessels," he explains. These foods include garlic, onions, ginger and cayenne, a hot red pepper. to three setvings of fruits and thtee to fout setvings of vegetables a day, get only about 190 micrograms of folate a day. As fot B6, men get about 1.9 milligtams and women get about 1.

Principles and Practice of Phytotherapy: Modern Herbal Medicine

Simon Mills and Kerry Bone
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Time-dependent diuretic response in rats treated with juniper berry preparations. phytotherapy research 1998; 12: 494-497. 62. Schilcher H, Leuschner F. Studies of potential nephrotoxic effects of essential juniper oil (German). Arzneimittel-Forschung 1997; 47 (7): 855-858. 63. Dorow P, Weiss TH, Felix R et al. Effect of a secretolytic and a combination of pinene, limonene and cineole on mucociliary clearance in patients with chronic pulmonary obstruction. Arzneimittel-Forschung 1987; 37 (12): 1378-1381. 64. Boyd EM. Expectorants and respiratory tract fluid.

The Encyclopedia of Popular Herbs

Robert S. McCaleb, Evelyn Leigh, and Krista Morien
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Aloe vera: antiulcer and antidiabetic effects. phytotherapy research 1994; 8(8): 461-464. 12. Parmar MD,Tariq M, Al-Yahya MA, et al. Evaluation of aloe vera leaf exudate and gel for gastric and duodenal ulcer activity. Fitoterapia 1986; 57(5): 380-383. 13. Wang HH, Chung JG. Emodin-induced inhibition of growth and DNA damage in the Helicobacter pylori. Current Microbiology 1997;35: 262-266. 14. Wang HH, Chung JG, Ho CC. Aloe-emodin effects on arylamine n-acetyltransferase activity in the bacterium Helicobacter pylori. Planta Medica 1998; 64: 176-178. 15. Atherton P. Aloe vera revisited.
Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: a double-blind placebo-controlled study. phytotherapy research 1997; 2: 508-11. 3. Murphy JJ, Heptinstall S, Mitchell JRA. Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. The Lancet July 23, 1988; 189-92. 4. Robbers JE,Tyler VE. Tyler's Herbs of Choice. New York and London: The Haworth Press, Inc., 1999. 5. Heptinstall S, Awang DVC. Feverfew: a review of its history, its biological and medicinal properties, and the status of commercial preparations of the herb.

Alternative Medicine the Definitive Guide, Second Edition

Larry Trivieri, Jr.
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Director of the American phytotherapy research Laboratory, in Lehi, Utah. Dr. Mowrey believes that putting aside the old concept of weight management in favor of fat management is more useful.40 There are a number of ways of measuring body fat, all of which are generally performed in a physician's office, health club, or weight-loss clinic. One method uses calipers to measure skinfold thickness at various points on the body.

The Woman's Encyclopedia of Natural Healing

Dr. Gary Null
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Assessment of the Hypnotic/Sedative Effects and Toxicity of Passiflora Edulis Aqueous Extract in Rodents and Humans," phytotherapy research 5 (1991): 262-66. Animal research showed Harpagophytum procum-bensto have anti-inflammatory and analgesic effects. At 200 mg/kg, its effect was similar to a 68-mg/kg dose of the analgesic acetylsalicylic acid (aspirin). M. C. Lanhers et al., "Anti-Inflammatory and Analgesic Effects of an Aqueous Extract of Harpagophytum Procum-bens," Planta Med. 58 (1992): 117-123.
Antidiabetic and Adaptogenic Properties of Momordica Charantia Extract: An Experiment and Clinical Evaluation," phytotherapy research 7 (1993): 285-89. Researchers found that in type II diabetics, 50 ml/day of bitter melon juice significantly reduced concentrations of blood glucose, and that a smaller yet still significant effect resulted from daily consumption of fried bitter melon as well. B. A. Leatherdale et al., "Improvements in Glucose Tolerance Due to Momordica Charantia (Karela)," British Medical Journal 282 (1981): 1823-24. A topical 0.
Against Influenza and Herpes Simplex Viruses," phytotherapy research 4, no. 3 (1990): 97-100. The Chinese herbal medicine kanzo-bushi-to was shown, in mice, to help the immune system fight herpes. R. Matsuo et al., "Effects of a Traditional Chinese Herbal Medicine, Kanzo-Bushi-to, on the Resistance of Thermally Injured Mice Infected with Herpes Simplex Virus Type 1," International Journal of Immunopharmacology 16, no. 10 (1994): 855-63.

Prevention's Healing With Vitamins : The Most Effective Vitamin and Mineral Treatments for Everyday Health Problems and Serious Disease

The Editors of Prevention Magazine Health Books
See book keywords and concepts
American phytotherapy research Laboratory in Lehi, Utah. Although ginger ale or ginger tea may calm your tummy, the powdered stuff packs the most punch, says Jennifer Niebyl, M.D., professor and head of obstetrics and gynecology at the University of Iowa College of Medicine in Iowa City. "The usual dosage is about a half-teaspoon," she says. Ginger has no known adverse side effects, she adds. Graze and pick. "Eating frequent light meals that are rich in carbohydrates and low in fat may help your nausea, so it's worth a try," says Dr. Niebyl.

Principles and Practice of Phytotherapy: Modern Herbal Medicine

Simon Mills and Kerry Bone
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Confirmation that tannin-containing crude drugs have a uraemic toxin-decreasing action. phytotherapy research 1995; 9:1-5. 128. Akah PA. Haemostatic activity of aqueous leaf extract of Ageratum conyzoides L. International Journal of Crude Drug Research 1988; 26 (2): 97-101. 129. Root-Bernstein RS. Tannic acid, semipermeable membranes and burn treatment. Lancet 1982; 2:1168. 130. Haslam E. Natural polyphenols (vegetable tannins) as drugs: possible modes of action. Journal of Natural Products 1996; 59: 205-215. 131. Okuda T, Yoshida T, Hatano T.
A safe and effective drug. phytotherapy research 1998; 12: S143-S145. 213. Nijs G, De Witte P, Geboes K et al. In vitro demonstration of a positive effect of rhein anthrone on peristaltic reflex of guinea pig ileum. Pharmacology 1993; 47 (supp 1): 40-48. 214. Leng-Peschlow E. Sennoside-induced secretion is not caused by changes in mucosal permeability or Na(+), K(+)-ATPase activity. Journal of Pharmacy and Pharmacology 1993; 45 (11): 951-954. 215. Yagi T, Miyawaki Y, Nishikawa A et al.

Symptoms: Their Causes & Cures : How to Understand and Treat 265 Health Concerns

the Editors of PREVENTION Magazine Health Books
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American phytotherapy research Laboratory in Salt Lake City. Come up on deck. Enclosed spaces aggravate motion sickness. And once on deck, you should stand near the center of the ship, where there is less pitching motion, says R. J. Oenbrink, D.O., a physician in private practice in Tequesta, Florida, who often works on ships. Keep your eyes on the level. On a boat, keep your eyes on the horizon. In a car, focus on the distant terrain ahead of you. It's helpful to stabilize your vision even though your inner ears are registering a lot of motion, says Dr. Koch. Press your wrist.

The Clinician's Handbook of Natural Healing

Gary Null, Ph.D.
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Lievoux, "Clinical Studies on the Palliative Treatment of Prostatic Adenoma with Extract of Urtica Root," phytotherapy research, 5, 1991, p. 267-269. ¦ SUNFLOWER Cardiovascular/Coronary Heart Disease Results of this study found that intake of a linoleic acid-rich diet, applying 12% sunflower seed oil in rat food pellet for 4 weeks, decreased the occurrence of life-threatening arrhythmias both during the acute phase of myocardial ischemia and during reperfusion in anesthetized rats. —I. Lepran & L.

The Encyclopedia of Popular Herbs

Robert S. McCaleb, Evelyn Leigh, and Krista Morien
See book keywords and concepts
Effect of garlic and garlic preparations on physiological and psychological stress in mice. phytotherapy research 1997; 2: 226-230. 41. Moriguchi T, Saito J, Nishiyama N. Anti-ageing effect of aged garlic extract in the inbred brain atrophy mouse model. Clinical and Experimental Pharmacology and Physiology 1997;24: 235-242. 42. Gebhardt R. Multiple inhibitory effects of garlic extracts on cholesterol biosynthesis in hepatocytes. Lipids 1993; 28(7): 613-619. 43. Sheela CG, Augusti KT.

The Clinician's Handbook of Natural Healing

Gary Null, Ph.D.
See book keywords and concepts
Yamasaki,' 'Garlic Compounds Protect Vascular Endothelial Cells from Hydrogen Peroxide-Induced Oxidant Injury," phytotherapy research, 8, 1994, p. 408-412. Results of this study found that alloxan diabetic rats orally administered a combination of onion, garlic, sulfoxide amino acids, S-methylycsteine sulfoxide, and S-allycysteine sulfoxide experienced an amelioration of symptoms relative to rats treated with glibebclamide and insulin. —C.G. Sheela, et al., "Anti-diabetic Effects of Onion and Garlic Sulfoxide Amino Acids in Rats," Planta Med, 61, 1995, p. 356-357.
Aerial Parts of Hypericum Perforatum, L, and Roots of Saponaria Offinalis L against Influenza and Herpes Simplex Viruses," phytotherapy research, 4(3), 1990, p. 97-100. ¦ STINGING NETTLE Benign Prostatic Hyperplasia This study examined the effects of organic-solvent extracts of Urtica dioica (Urticaceae) on the Na+, K(+)- ATPase of the tissue of benign prostatic hyperplasia (BPH) were investigated.

The Complete Book of Alternative Nutrition

Selene Y. Craig, Jennifer Haigh, Sari Harrar and the Editors of PREVENTION Magazine Health Books
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American phytotherapy research Laboratory in Salt Lake City. "There's a lot more research that needs to be done." If you would like to include herbs in your personal cancer prevention strategy, it's important to have a realistic sense of what these plants might be able to do and what's better left to conventional medical treatment, cautions Dr. Mowrey. Remember that when it comes to cancer, herbal nutrition is probably more effective as a preventive measure than as a cure.

The Encyclopedia of Popular Herbs

Robert S. McCaleb, Evelyn Leigh, and Krista Morien
See book keywords and concepts
Clinical studies on the palliative treatment of prostatic adenoma with extract of Urtica root. phytotherapy research 1991; 5: 267-269. 11. Stahl HP. The treatment of prostatic nycturia with standardized extract of Radix Urticae (ERU) [in German]. Zeitschrift All-gemeiner Medizin 1984; 60: 128-132. 12. Dathe G, Schmid H. Phytotherapy for benign prostatic hyperplasia (BPH): double-blind study with extract Radicus Urticae (ERU) [in German]. Urologe B 1987; 27: 223-226. 13. Berges RR, Windeler J, Trampisch HJ, et al.

The Woman's Encyclopedia of Natural Healing

Dr. Gary Null
See book keywords and concepts
Assessment of the Hypnotic/Sedative Effects and Toxicity of Passiflora Edulis Aqueous Extract in Rodents and Humans," phytotherapy research 5 (1991): 262-66. Animal research showed Harpagophytum procum-bensto have anti-inflammatory and analgesic effects. At 200 mg/kg, its effect was similar to a 68-mg/kg dose of the analgesic acetylsalicylic acid (aspirin). M. C. Lanhers et al., "Anti-Inflammatory and Analgesic Effects of an Aqueous Extract of Harpagophytum Procum-bens," Planta Med. 58 (1992): 117-123.
Against Influenza and Herpes Simplex Viruses," phytotherapy research 4, no. 3 (1990): 97-100. The Chinese herbal medicine kanzo-bushi-to was shown, in mice, to help the immune system fight herpes. R. Matsuo et at, "Effects of a Traditional Chinese Herbal Medicine, Kanzo-Bushi-to, on the Resistance of Thermally Injured Mice Infected with Herpes Simplex Virus Type 1," International Journal of Immunopharmacology 16, no. 10 (1994): 855-63.
Antidiabetic and Adaptogenic Properties of Momordica Charantia Extract: An Experiment and Clinical Evaluation," phytotherapy research 7 (1993): 285-89. Researchers found that in type II diabetics, 50 ml/day of bitter melon juice significantly reduced concentrations of blood glucose, and that a smaller yet still significant effect resulted from daily consumption of fried bitter melon as well. B. A. Leatherdale et al., "Improvements in Glucose Tolerance Due to Momordica Charantia (Karela)," British Medical Journal 282 (1981): 1823-24. A topical 0.

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